Micronucleus Test - in vitro CBMN Test
Micronucleus Test - in vitro CBMN Test

Art. No.:
SSA-O487

Unit
Service Analytics for 1 - X Compounds
Description

Service anayltics with in Vitro Mammalian Cell Micronucleus Test (MNT) according to OECD487 under GLP and non GLP conditions. The MNT is used for the  screening of test compounds for gentoxic activity by measuring micronuclei formed during exposure to test compound. The test is used for  in vitro toxicological risk assessment of chemicals, pesticides, cosmetics, plant extracts.

Characteristics

  • The test can be performed in primary human peripheral blood lymphocytes (HPBLs) or in TK6 cells, translocation of the test system to other cell lines is also offered.
  • The experiments are performed in the presence and absence of post mitochondrial supernatant (S9) 
  • Qualitative and quantitative approach
  • Can be combined with telomer and centromer staining for increased sensitivity 
  • Allows discrimination between aneugenic and clastogenic compounds if combined with Telomer and Centromer Staining

 


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Service Analytics Leaflet

Service Analytics for Genotoxicity Leaflet