Ex vivo Bovine Nail Sheet serves as a model for in vitro permeation tests, absorption or penetration safety studies of chemicals, agrochemicals, topically applied pharmaceuticals, cosmetics, biocides, pesticides. The discs can be used for the safety assessment according to OECD 428, EFSA, EMA, FDA guidelines and MDR 2017/745.
Bovine Nail Sheets, XenoSkin H discs and porcine mucosas are excellent in vitro models for selecting drug candidates for dermal application, characterization of topical dosage forms, quality and safety assessment, selecting a suitable transdermal vehicle or classification of a substance based medical device. Ex vivo nail sheets are full in line with 3R and are replacing test animals.
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