XenoSkin P BM 8 mm Disk - Oral Full Thickness Porcine Buccal Mucosa Model for in vitro Permeation Testing in line with 3R Concept

Art. No.: PBM-F20D-8

8mm Ø Disk - Frozen Full Thickness Pig Buccal Mucosa

Product Description
Documents (2)

XenoSkin P BM is an ex vivo Porcine Buccal Mucosa disk model available as dermatomed or full thickness membrane disk for in vitro oral evaluation of drug permeability (IVPT), dermal absorption or penetration safety studies of chemicals, agrochemicals, pharmaceuticals or biocides and pesticides according to OECD TG428, MDR 2017/745, EU No 528/2012, EFSA. XenoSkin P BM mucosa models are also used in place of colon mucosa or vaginal mucosa models. The porcine skin explants are an excellent model for in vitro skin permeation testing (IVPT) studies. The models are in line with 3R : Reduce, Refine, Replace Animal Testing.

Characteristics of ex vivo Pig Mucosa Models for in vitro Skin Permeation Testing IVPT

Full thickness mucosa model
aproved for standard health care tests for slaughterhouse animals
time form slaughterhouse to preparation in the lab < 6 hours
macroscopic examination
mean thickness of dermatomed mucosa: 700 - 1000 µm
mean thickness of full thickness mucosa model: 1800 - 2000 µm
in line with 3Rs : Reduce, Refine, Replace Animal Testing
different other sizes are available, please contact info@xenometrix.ch
for porcine nasal mucosa please contact info@xenometrix.ch
can also serve as vaginal model
in line with OECD 428, EU Regulation 2017/745, Rule 21 for classification of medical devices, EFSA, EMA and FDA guidelines
Skin Absorption/Permeation analytical services available on skin explants or on 3D organotypic tissue models (skin, oral, vaginal, corneal, bladder, colorectal, nasal, intestinal tissues), please contact info@xenometrix.ch
for prices please contact info@xenometrix.ch

Other ex vivo Skin Models and IVPT services

Ex vivo dermatomed or full thickness porcine ear skin
Ex vivo single bovine nail sheets
Ex vivo dermatomed human skin (abdominal, face)
Ex vivo full thickness human skin (abdominal, face)
Franz diffusion cells, jacketed and unjacketed in many different sizes
Skin Absorption/Permeation study services available on skin explants or on 3D organotypic tissue models (skin, oral, vaginal, corneal, bladder, colorectal, nasal, intestinal tissues), please contact info@xenometrix.ch

XenoSkin Leaflet

Leaflets

XenoSkin Leaflet

Service Analytics Genotoxicity

Service Analytics Genotoxicity