Ex vivo dermatomed Skin Model, 5 mm Disk for in vitro Permeation Testing IVPT, in vitro dermal Absorption or Skin Penetration, OECD TG428, MDR 2017/745

Art. No.: H-D20D-5

5mm Ø Disks - Frozen Dermatomed Human ex vivo Abdominal Skin Model XenoSkin H

Product Description
Documents (2)

XenoSkin H is an ex vivo human skin model available as dermatomed or full thickness membrane disc for in vitro skin permeation testing, dermal absorption or penetration safety studies of chemicals, agrochemicals, pharmaceuticals, cosmetics or biocides and pesticides according to OECD TG428, MDR 2017/745, EU No 528/2012, EFSA. The ex vivo skin models are from left over skin after cosmetic surgery from donors who gave their informed consent. They are prepared under high quality standards. XenoSkin H ex vivo skin models are also used for selecting drug candidates for dermal application, characterization of topical dosage forms, quality assessment, selecting a suitable transdermal vehicle. XenoSkin H is an excellent in vitro model for in vitro skin permeation testing (IVPT) studies and is replacing many test animals.

Characteristics of ex vivo Skin Models for in vitro Skin Permeation IVPT

abdominal or face ex vivo human skin models
aproved for absence of HCV, HIV-1, HIV-2
In line with OECD TG428, MDR 2017/745, EFSA
time from surgery to lab < 6 hours
macroscopic examination for absence of scars, surgical markers or pubic hairs
thickness 300 - 500 µm
in line with 3Rs (Reduce, Refine, Replace), replacing animal tests
many different diameters
Analytical services for in vitro dermal permeation testing is available under GLP and non GLP
For prices of the discs or of analytical services please contact info@xenometrix.ch