Ames MPF

Ames MPF
  • Christen et al. 1996. "[24] Mutagenicity of nitric oxide in base pair-specific Salmonella tester strains: TA7000 series". Methods Enzymol. 269:267–78. DOI:10.1016/S0076-6879(96)69027-2.
  • Flueckiger-Isler et al. 2004. "Assessment of the performance of the Ames II™ assay: A collaborative study with 19 coded compounds". Mutat Res. 558(1–2):181–97. DOI:10.1016/j.mrgentox.2003.12.001.
  • Flueckiger-Isler and Kamber. 2012. "Direct comparison of the Ames microplate format (MPF) test in liquid medium with the standard Ames pre-incubation assay on agar plates by use of equivocal to weakly positive test compounds". Mutat Res. 747(1):36–45. DOI:10.1016/j.mrgentox.2012.03.014.
  • Gee et al. 1994. "Detection and classification of mutagens: A set of base-specific Salmonella tester strains". PNAS USA. 91(24):11606–10. DOI:10.1073/pnas.91.24.11606.
  • Gee et al. 1998. "Comparison of responses of base-specific Salmonella tester strains with the traditional strains for identifying mutagens: The results of a validation study". Mutat Res. 412(2):115–30. DOI:10.1016/S1383-5718(97)00172-1.
  • Kamber et al. 2009. "Comparison of the Ames II and traditional Ames test responses with respect to mutagenicity, strain specificities, need for metabolism and correlation with rodent carcinogenicity". Mutagenesis. 24(4):359–66. DOI:10.1093/mutage/gep017.
  • Piegorsch et al. 2000. "Statistical modeling and analyses of a base-specific Salmonella mutagenicity assay". Mutat Res. 467(1):11–9. DOI:10.1016/S1383-5718(00)00019-X.
  • Reifferscheid et al. 2012. "International round‐robin study on the Ames fluctuation test". Environ Mol Mutagen. 53(3):185–97. DOI:10.1002/em.21677.
  • Umbuzeiro Gde et al. 2010. "Comparison of the Salmonella/microsome microsuspension assay with the new microplate fluctuation protocol for testing the mutagenicity of environmental samples". Environ Mol Mutagen. 51(1):31–8. DOI:10.1002/em.20504.
C60 fullerene
  • Borowik et al. 2018. "Does C60 fullerene act as a transporter of small aromatic molecules?". Colloids Surf B Biointerfaces. 164:134–43. DOI:10.1016/j.colsurfb.2018.01.026.
  • Prylutskyy et al. 2016. "Biophysical characterization of the complexation of C60 fullerene with doxorubicin in a prokaryotic model". Mat-wiss u Werkstofftech. 47:2–3. DOI:10.1002/mawe.201600463.
  • Leighfield et al. 2009. "Brevetoxin B is a clastogen in rats, but lacks mutagenic potential in the SP-98/100 Ames test". Toxicon. 54(6):851–856. DOI:10.1016/j.toxicon.2009.06.018.
  • Oztas et al. 2015. "In vitro investigation on the toxic potentials of commonly used synthetic pyrethroids, especially esbiothrin". Appl In Vitro Toxicol. 1(4):302–7. DOI:10.1089/aivt.2015.0022.
  • Titaley et al. 2016. "Identification and toxicological evaluation of unsubstituted PAHs and novel PAH derivatives in pavement sealcoat products". Environ Sci Technol Lett. 3(6):234–42. DOI:10.1021/acs.estlett.6b0011.6.
  • Barbezan et al. 2017. "Ames test to detect mutagenicity of 2‐alkylcyclobutanones: A review". J Food Sci. 82(7):1518–22. DOI:10.1111/1750-3841.13721. [review]
  • Lewandowska et al. 2014. "Isothiocyanates may chemically detoxify mutagenic amines formed in heat processed meat". Food Chem. 157:105–10. DOI:10.1016/j.foodchem.2014.01.082.
  • Bandyopadhyay-Ghosh et al. "Biosynthesis, microstructural characterisations and investigation of in-vitro mutagenic and eco-toxicological response of a novel microbial exopolysaccharide based biopolymer". J Polym Environ. 26(1):365–74. DOI:10.1007/s10924-016-0925-x.
  • Harvey et al. 2017. "Synthesis and characterization of a high temperature thermosetting polyimide oligomer derived from a non-toxic, sustainable bisaniline". RSC Adv. 37:23149–56. DOI:10.1039/C7RA02182H.
  • Major et al. 2017. "Effects of the surface modification of polyurethane substrates on genotoxicity and blood activation processes". Mater Sci Eng C Mater Biol Appl. 79:756–62. DOI:10.1016/j.msec.2017.05.060.
  • More et al. 2013. "Genotoxicity and Mutagenicity Evaluation of Polyethylene Sebacate Nanoparticles". J Nanopharm Drug Deliv. 1(3):301–10. DOI:10.1166/jnd.2013.1023.
  • More et al. 2009. "Polyethylene sebacate: Genotoxicity, mutagenicity evaluation and application in periodontal drug delivery system". J Pharm Sci. 98(12):4781–95. DOI:10.1002/jps.21796.
  • Skrzypczak et al. 2012. "Influence of titanium dioxide on the photo-genotoxicity of selected sunscreens under UVA and UVB irradiation investigated with umu-test and Ames MPF™ assay". Fresen Environ Bull. 21(12):3796–803. DOI:__
  • Adebola et al. 2013 "Protective effects of prebiotics inulin and lactulose from cytotoxicity and genotoxicity in human colon adenocarcinoma cells". Food Res Intl. 52(1):269–74. DOI:j.foodres.2013.03.024.
  • Chung et al. 2000. "Comparison of the mutagenic specificity induced by four nitro-group-containing aromatic amines in Salmonella typhimurium his genes". Mutat Res. 465(1–2):165–71. DOI:10.1016/S1383-5718(99)00225-9.
  • Claxton et al. 2001. "Using base-specific Salmonella tester strains to characterize the types of mutation induced by benzidine and benzidine congeners after reductive metabolism". Food Chem Toxicol. 39(12):1253–61. DOI:10.1016/S0278-6915(01)00072-2.
  • Cornwell et al. 2002. "Mutagenicity of tocopheryl quinones: evolutionary advantage of selective accumulation of dietary a-tocopherol". Nutr Cancer. 43:111–8. DOI:10.1207/S15327914NC431_13.
  • Erkekoglu et al. 2017. "The mutagenic potential of 3,5-dimethylaminophenol in bacterial and mammalian cells". FABAD J Pharm Sci. 42(2):87-93. DOI:__
  • Golunski et al. 2013. "Modulation of acridine mutagen ICR191 intercalation to DNA by methylxanthines – Analysis with mathematical models". Bioorg Med Chem. 21(11):3280–9. DOI:10.1016/j.bmc.2013.03.043.
  • Murata-Kamiyaa et al. 1997. "Types of mutations induced by glyoxal, a major oxidative DNA-damage product, in Salmonella typhimurium". Mutat Res. 377(1):13–6. DOI:10.1016/S0027-5107(97)00016-X.
  • Regulska et al. 2014. "The mutagenicity analysis of imidapril hydrochloride and its degradant, diketopiperazine derivative, nitrosation mixtures by in vitro Ames test with two strains of Salmonella typhimurium". Rep Pract Oncol Radiother. 19(6):412–9. DOI:10.1016/j.rpor.2014.04.004.
  • Schrader et al. 2002. "Mutagenicity of bisphenol A (4,4′‐isopropylidenediphenol) in vitro: effects of nitrosylation". Teratogenesis Carcinog Mutagen. 22:425–41. DOI:10.1002/tcm.10039.
  • Sieroslawska. 2013. "Assessment of the mutagenic potential of cyanobacterial extracts and pure cyanotoxins". 74:1-7. DOI: 10.1016/j.toxicon.2013.07.029.
  • Williams et al. 2011. "Toxicologic characterization of a novel explosive, triaminoguanidinium-1-methyl-5-nitriminotetrazolate (TAG-MNT), in female rats and in vitro assays". J Toxicol Environ Health Sci. 3(3):80–94. DOI:__
  • Smith et al. 2013. "The dosing determines mutagenicity of hydrophobic compounds in the Ames II assay with metabolic transformation: Passive dosing versus solvent spiking". Mutat Res. 750(1–2):12–8. DOI:10.1016/j.mrgentox.2012.07.006.
  • Abdelsamie et al. 2017. "Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC50 for a proof-of-principle study". Eur J Med Chem. 127:944–57. DOI:10.1016/j.ejmech.2016.11.004.
  • Alachkar et al. 2018. "Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats". Pharmacol Biochem Behav. 170:14–24. DOI:10.1016/j.pbb.2018.04.010.
  • Altintop et al. 2012. "Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents". Eur J Med Chem. 58:299–307. DOI:0.1016/j.ejmech.2012.10.011.
  • Altintop et al. 2015. "A novel series of thiazolyl–pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity". Eur J Med Chem. 92:342–52. DOI:10.1016/j.ejmech.2014.12.055.
  • Altintop et al. 2016. "Synthesis and biological evaluation of new naphthalene substituted thiosemicarbazone derivatives as potent antifungal and anticancer agents". Eur J Med Chem. 108:406–14 DOI:10.1016/j.ejmech.2015.11.041.
  • Altintop et al. 2016. "Synthesis and evaluation of new thiazole derivatives as potential antimicrobial agents". Lett Drug Des Discov. 13(9):903–11. DOI:10.2174/1570180813666160226001021.
  • Al-Serori et al. 2016. "Investigations of the genotoxic properties of twosynthetic cathinones (3-MMC, 4-MEC) which are used as psychoactive drugs". Toxicol Res. 5:1410–20. DOI:10.1039/C6TX00087H.
  • Benes et al. 2012. "Redox state alters anti‐cancer effects of wedelolactone". Environ Mol Mutagen. 53(7):515–24. DOI:10.1002/em.21712.
  • Can et al. 2017. "Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors". Eur J Med Chem. 144:68-81. DOI:1016/j.ejmech.2017.12.013.
  • Cardoso et al. 2006. "In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives". Eur J Med Chem. 41(3):408–16. DOI:10.1016/j.ejmech.2005.10.019.
  • Dabrowska-Mas and Ras. 2017. "Metronidazole citrate ester as the new prodrug of metronidazole". Curr Chem Lett. 6(4):167–76. DOI:10.5267/j.ccl.2017.6.002.
  • Domaradzka et al. 2016."Toxicity of diclofenac and its biotransformation by Raoultella DD4". Pol J Environ Stud. 25(5):2211–6. DOI:10.15244/pjoes/62681.
  • Emerce et al. 2015. "Determination of the impurities in drug products containing montelukast and in silico/in vitro genotoxicological assessments of sulfoxide impurity". Toxicol Lett. 238(2): 90–9. DOI:10.1016/j.toxlet.2015.07.003.
  • Emerce et al. 2016. "An investigation of the mutagenic activity of salamide – a major impurity of hydrochlorothiazide". Toxicol Mech Methods. 26(9):644–9. DOI:10.1080/15376516.2016.1222642.
  • Emmerich et al. 2017. "Lead optimization generates CYP11B1 inhibitors of pyridylmethyl isoxazole type with improved pharmacological profile for the treatment of Cushing’s disease". J Med Chem. 60(12):5086–98. DOI:10.1021/acs.jmedchem.7b00437.
  • Erguc et al. 2018. "Synthesis and biological evaluation of new quinoline-based thiazolyl hydrazone derivatives as potent antifungal and anticancer agents". Lett Drug Des Discov. 15(2):193–202. DOI:10.2174/1570180814666171003145227.
  • Ferk et al. 2016. "Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4". Arch Toxicol. 90(12):3111–23 DOI:0.1007/s00204-016-1664-4
  • Golunski et al. 2016. "Pentoxifylline affects idarubicin binding to DNA". Bioorg Chem. 65:118–25. DOI:10.1016/j.bioorg.2016.02.005.
  • Golunski et al. 2016. "Pentoxifylline as a modulator of anticancer drug doxorubicin. Part II: Reduction of doxorubicin DNA binding and alleviation of its biological effects". Biochimie. 123:95–102. DOI:10.1016/j.biochi.2016.02.003.
  • Karayildirim et al. 2018. "Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative". Saudi Pharm J. 26(3):369–74. DOI:1016/j.jsps.2018.01.004.
  • Kirf et al. 2010. "Cyto- and genotoxicological assessment and functional characterization of N-vinyl-2-pyrrolidone–acrylic acid-based copolymeric hydrogels with potential for future use in wound healing applications". Biomed Mater. 5(3):35002. DOI:10.1088/1748-6041/5/3/035002.
  • Koller et al. 2014. "Investigation of the in vitro toxicological properties of the synthetic cannabimimetic drug CP-47,497-C8". Toxicol Appl Pharmacol. 277:164–71. DOI:10.1016/j.taap.2014.03.014.
  • Koller et al. 2015. "Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids". Food Chem Toxicol. 80:130–6. DOI:10.1016/j.fct.2015.03.004.
  • Latacz et al. 2018. "MF-8, a novel promising arylpiperazine-hydantoin based 5-HT7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation". Bioorg Med Chem Lett. 28(5):878– DOI:10.1016/j.bmcl.2018.02.003.
  • Lazewska et al. 2018. "Novel naphthyloxy derivatives – Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation". Bioorg Med Chem. 26(9):2573–85. DOI:10.1016/j.bmc.2018.04.023.
  • Mahmoud et al. 2014. "Identification of phototransformation products of thalidomide and mixture toxicity assessment: An experimental and quantitative structural activity relationships (QSAR) approach". Water Res. 49:11–22. DOI:10.1016/j.watres.2013.11.014.
  • Mulla et al. 2012. "Mutagenicity and clastogenicity evaluation of tacrine by Ames and micronucleus assays". Drug Chem Toxicol. 35(4):366–70. DOI:10.3109/01480545.2011.627865.
  • Nesterenko et al. 2016. "A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones suppresses Salmonella infection in vivo". J Antibiot (Tokyo). 69(6):422–7. DOI:10.1038/ja.2015.131.
  • Ramires et al. 2005. "In vitro and in vivo biocompatibility evaluation of a polyalkylimide hydrogel for soft tissue augmentation". J Biomed Mater Res B Appl Biomater. 72(2):230–8. DOI:10.1002/jbm.b.30157.
  • Ranganatha et al. 2015. "High-throughput approaches for genotoxicity testing in drug development: recent advances". Int J High Throughput Screen. 6:1-12. DOI:2147/IJHTS.S70362. [review]
  • Vanda et al. 2017. "Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties". Eur J Med Chem. 144:716–29. DOI:1016/j.ejmech.2017.12.053.
  • Witek et al. 2017. "Selenazolinium salts as “small molecule catalysts” with high potency against ESKAPE bacterial pathogens". 22(12):2174. DOI: 10.3390/molecules22122174.
  • Zur et al. 2018. "Paracetamol – toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring degradation pathway". Chemosphere. 206: 192-202. DOI:10.1016/j.chemosphere.2018.04.179.
  • Toolaram et al. 2016. "Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing". Environ Pollut. 211:148–56. DOI:10.1016/j.envpol.2015.12.040.
  • Agarwal et al. 2018. "Toxicity and mutagenicity of exhaust from compressed natural gas: Could this be a clean solution for megacities with mixed-traffic conditions?". Environ Pollut. 239: 499–511. DOI:1016/j.envpol.2018.04.028.
  • Erdinger et al. 2004. "Analysis of mutagenic activity of airborne particulate matter, standard reference materials and reference compounds using base pair-specific Salmonella typhimurium tester strains". Mutat Res. 564(2):149–57. DOI:10.1016/j.mrgentox.2004.08.002.
  • Gurbani et al. 2013. "Polycyclic aromatic hydrocarbons and their quinones modulate the metabolic profile and induce DNA damage in human alveolar and bronchiolar cells". Int J Hyg Environ Health. 216(5):553–65. DOI:10.1016/j.ijheh.2013.04.001.
  • Kozlowska et al. 2012. "Microplate Ames MPF test use in assessment of mutagenic properties of dust pollution". Medycyna Środowiskowa. 15(3):55–65. DOI:__
  • Miller et al. 1998. "Urinary and serum mutagenicity studies with rats implanted with depleted uranium or tantalum pellets". Mutagenesis. 13(6):643–8. DOI:10.1093/mutage/13.6.643.
  • Morais Leme et al. 2012. "An overview of biodiesel soil pollution: Data based on cytotoxicity and genotoxicity assessments". J Hazard Mater. 199–200:343–9. DOI:10.1016/j.jhazmat.2011.11.026.
  • Morais Leme et al. 2012. "Genotoxicity assessment of water soluble fractions of biodiesel and its diesel blends using the Salmonella assay and the in vitro MicroFlow® kit (Litron) assay". Chemosphere. 86(5):512–20. DOI:10.1016/j.chemosphere.2011.10.017.
  • Parker et al. 2017. "UV/H2O2 advanced oxidation for abatement of organophosphorous pesticides and the effects on various toxicity screening assays". 182:477–82. DOI:10.1016/j.chemosphere.2017.04.150.
  • Steiner et al. 2014. "Effects of an iron-based fuel-borne catalyst and a diesel particle filter on exhaust toxicity in lung cells in vitro". Anal Bioanal Chem. 20:5977–86. DOI:10.1007/s00216-014-7878-5.
  • Steiner et al. 2014. "Test-methods on the test-bench: a comparison of complete exhaust and exhaust particle extracts for genotoxicity/mutagenicity assessment". Environ Sci Technol. 48(9):5237–44. DOI:10.1021/es4056033.
  • van den Heuvel et al. 2018. "Toxicity of urban PM10 and relation with tracers of biomass burning". Int J Environ Res Public Health. 15(2):DOI:10.3390/ijerph15020320.
  • Wang et al. 2011. "Concentration and photochemistry of PAHs, NPAHs, and OPAHs and toxicity of PM5 during the Beijing Olympic Games". Environ Sci Technol. 45(16):6887–95. DOI:10.1021/es201443z.
  • Wieczerzak et al. 2016. "Bioassays as one of the Green Chemistry tools for assessing environmental quality: A review". Environm Int. 94:341–61. DOI:10.1016/j.envint.2016.05.017. [review]
  • Abudayyak et al. 2015. "Investigation on the toxic potential of Tribulus terrestris in vitro". Pharm Biol. 53(4):469–76. DOI:10.3109/13880209.2014.924019.
  • Abudayyak et al. 2015. "Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey". Turk J Med Sci. 45(3):496–506. DOI:10.3906/sag-1401-153.
  • Baskaran et al. 2018. "Genotoxic evaluation of Rasagenthi Mezhugu, a Siddha formulation, using Salmonella typhimurium strains". Int J Res BioSciences. 7(1):70–6. DOI:__
  • Boddapati et al. 2018. "Mutagenicity and acute oral toxicity test for herbal poultry feed supplements". J Toxicol. 2018:Article ID 9412167. DOI:10.1155/2018/9412167.
  • Chandrasekaran et al. 2009. "Evaluation of the genotoxic potential and acute oral toxicity of standardized extract of Andrographis paniculata (KalmCold™)". Food Chem Toxicol. 47(8):1892–902. DOI:10.1016/j.fct.2009.05.006.
  • Chandrasekaran et al. 2010. "In vitro efficacy and safety of poly-herbal formulations". Toxicol In Vitro. 24(3):885–97. DOI:10.1016/j.tiv.2009.11.021.
  • Chandrasekaran et al. 2011. "Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™)". Regul Toxicol Pharmacol. 61(3):373–80. DOI:10.1016/j.yrtph.2011.10.002.
  • Katebale et al. 2017. "Phytochemical screening, cytotoxic, genotoxic and mutagenic effects of the aqueous extract of Azadirachta indica leaves". Int J Herb Med. 5(3):39–44. E-ISSN:2321-2187.
  • Saxena et al. 2017. "No induced mutagenesis in human lymphoblast cell line and bacterial systems upon their prolonged sub‐culturing in irradiated food blended media". J Sci Food Agricult. 98(5):2011–9. DOI:1002/jsfa.8686.
  • Saxena et al. 2012. "Suppression of error prone pathway is responsible for antimutagenic activity of honey.". Food Chem Toxicol. 50(3–4):625–33. DOI:10.1016/j.fct.2012.01.003.
  • Zappa et al. 2009. "Feasibility study for the development of a toner-Reference Material". Measurements. 42(10):1491–6. DOI:10.1016/j.measurement.2009.08.006.
  • Balabanic et al. 2017. "Raw and biologically treated paper mill wastewater effluents and the recipient surface waters: Cytotoxic and genotoxic activity and the presence of endocrine disrupting compounds". Sci Tot Environm. 574:78–89. DOI:10.1016/j.scitotenv.2016.09.030
  • Heringa et al. 2011. "Formation and removal of genotoxic activity during UV/H2O2–GAC treatment of drinking water". Water Res. 45:366–74. DOI:10.1016/j.watres.2010.08.008.
  • Kolkman et al. 2013. "Sample preparation for combined chemical analysis and in vitro bioassay application in water quality assessment". Environ Toxicol Pharmacol. 36(3):1291–303. DOI:10.1016/j.etap.2013.10.009.
  • Martijn et al. 2015. "Induced genotoxicity in nitrate-rich water treated with medium-pressure ultraviolet processes (PDF)". AWWA. 107(6):E301–12. DOI:10.5942/jawwa.2015.107.0079.
  • Martijn et al. 2016. "Development of a 4-NQO toxic equivalency factor (TEF) approach to enable a preliminary risk assessment of unknown genotoxic compounds detected by the Ames II test in UV/H2O2 water treatment samples". 144:338–45. DOI:10.1016/j.chemosphere.2015.08.070.
  • Menz et al. 2016. "Transformation products in the water cycle and the unsolved problem of their proactive assessment: A combined in vitro/in silico approach". Environm Intl. 98:171–80. DOI:10.1016/j.envint.2016.11.003.
  • Mestankova et al. 2014. "Development of mutagenicity during degradation of N-nitrosamines by advanced oxidation processes". Water Res. 66:399–410. DOI:10.1016/j.watres.2014.08.012.
  • Pérez et al. 2003. "Assessment of the mutagenic potency of sewage sludges contaminated with polycyclic aromatic hydrocarbons by an Ames fluctuation assay". Environ Toxicol Chem. 22(11):2576–84. DOI:10.1897/02-416.
  • Reifferscheid et al. 2011. "Identification of mutagens in freshwater sediments by the Ames-fluctuation assay using nitroreductase and acetyltransferase overproducing test strains". Environ Mol Mutagen. 52(5):397–408. DOI:10.1002/em.20638.
  • Richard et al. 2014. "Toxicity of the micropollutants Bisphenol A, Ciprofloxacin, Metoprolol and Sulfamethoxazole in water samples before and after the oxidative treatment". Int J Hyg Environ Health. 217(4–5):506–14. DOI:10.1016/j.ijheh.2013.09.007.
  • Semitsoglou-Tsiapou et al. 2018. "Potential formation of mutagenicity by low pressure-UV/H2O2 during the treatment of nitrate-rich source waters". Environ Sci: Water Res Technol. __:__. DOI:10.1039/C7EW00389G.